Sunday, 18 September 2011

DURAL SINUS THROMBOSIS IN A PATIENT OF ULCERATIVE COLITIS





Axial FLAIR MR images and MR venograms showing acute infarcts in left cerebellar / left occipital regions due to thrombosis involving left transverse, left sigmoid sinuses along with left IJV.

Case history: 55 years old female with a long history of ulcerative colitis presenting with venous infarction due to dural sinus thrombosis.

Cerebral sinus thrombosis is an uncommon complication of ulcerative colitis( UC) in approximately 7.5%patients. It is probably due to genetic predisposition in combination with hypercoagulable state during relapse of UC.
It often presents with headaches and focal/ diffuse neurological signs.
It is important to be aware of this condition as it is a serious complication of inflammatory bowel disease with the potential of being fatal.

REFERENCE:
Nudelman RJ, Rosen DG, Rouah E, Verstovsek G. Cerebral Sinus Thrombosis: A Fatal Neurological Complication of Ulcerative Colitis.Pathology Research International: Volume 2010.

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